Nerve growth factor (NGF), belongs to protein, is a typical nerve nutrient substance with established chemical structure. Numerous studies have demonstrated that nerve growth factor is important for the growth, development, and maintenance of central and peripheral neurons under normal condition, protection after injury, and effective regeneration of axons. In 1986, Montalcini and Cohen won the Nobel physiological and medical prize for their outstanding contribution to the studyon NGF. Up to now, more than 3 million of new proteins and peptides have been found in the world, only ten of which has won the Nobel physiological and medical prize. However, only 3 of theabove tenhave become drugs: the achievement which won prize in 1901-antiserum therapy; the achievement which won prize in 1923-insulin; and the achievement which won prize in 1986-nerve growth factor. Nerve growth factor is the first and the only drug that firstly developed by Chinese and applied in clinical practice. Clinical application has confirmed that Nobex is the first choice to protect pericaryon and promote directional regeneration of axons.

For formulated granule of tradition Chinese medicine, authentic Chinese crude drug is processed according to traditional processing technology firstly. Then the extraction and separation technology for effective ingredients is made out according to the physico-chemical property, principle ingredients, and function of each ingredient. Granular formulation is produced by modernized pharmaceutical methods and dispensed according to clinical prescription. It is easy to be taken along and used by patients, easy to be dispensed and managed by the hospital, and helpful to realize the modernization of traditional Chinese medicine production. Moreover, it has increased the homogenicity, controllability, safety and hygieological index of quality, which is considered a revolution for decoction of traditional Chinese medicine.